The dry, high-desert climate of the Warm Springs Reservation differs substantially from the soggy conditions in Western Oregon. The humidity is low, and the sun shines almost every day. Overcast skies are rare. Generally, visitors can expect dry, sunny days and cool nights.

Temperatures on the Reservation vary from -38 degrees fahrenheit in the winter to 114 degrees fahrenheit in the summer. Elevation differences account for varying temperatures across the reservation. When the skies are clear, it is not uncommon for nighttime temperatures to differ from daytime temperatures by 30 to 40 degrees.

Annual precipitation on the Reservation, like temperature, varies according to elevation. On the western boundary, at the crest of the Cascades, annual precipitation is about 120 inches with annual snowfall of around 200 inches. On the eastern boundary, at the Deschutes River, annual precipitation is only about 10 inches with annual snowfall of around 15 inches.

The average growing season for Warm Springs is 140 days, from May 16 to October 3.